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'Unable to access Lotus Notes file C:\Program Files\IBM\Lotus\Notes\nnotes.dll. Please close all Lotus Notes applications and try again'
This error means something is still accessing nnotes.dll and has nothing to do with rights... Maybe you rebooted after changing to power user and that cleaned up the accesser...
Try using Process Explorer when you get this error to see what process is still accessging nnotes.dll